ʻO ka mea i hala koke iho nei, ua paʻi ʻia nā pepa noiʻi ʻelua, ʻo PMI a me BAT, i loko o nā puke moʻolelo olakino kiʻekiʻe.Hōʻike nā hualoaʻa noiʻi ʻo nā huahana paka hou e like me ka e-cigarettes a me nā huahana wela-not-burn ʻaʻole liʻiliʻi i ka pōʻino a me nā mea ʻawaʻawa ma mua o nā paka kahiko, a hiki ke hōʻemi nui i ka hopena i ka ʻōnaehana hanu.poino.
I ka hoʻonui ʻana o ka ʻike o ka poʻe i ka pōʻino o ka puhi paka, ua ʻike nui ʻia ka e-cigarette ma ke ʻano he pani no ka paka, akā ʻo ka hopena lōʻihi o ka hui ʻana i ka ʻono e-cigarette a me ka uahi paka ma luna o ka poʻe puhi paka.I kēia mau lā, ua paʻi ʻo PMI Philip Morris International i kahi hōʻike noiʻi "Assessment of inhalation toxicity o ka uahi paka a me nā aerosol mai nā hui ʻono: 5-week study in A/J mice" ma ka British Journal of Toxicology "Journal of Applied Toxicolog", e wehewehe ana i nā kikoʻī. o nā kumuhana pili Nā ʻanuʻu noiʻi a me nā hopena.
Ma ka hoʻokolohua, 87 mauʻiole kāne a me 174 nulliparous a hāpai wahine nāʻiole i randomly haawiia i 9 hoʻokolohua pūʻulu, a ua ho'āʻo 'ia i loko o ka lewa, paka paka, a me ka e-cigarette aerosols me ekolu okoa concentrations o flavorants, kiʻekiʻe, waena, a me ka haʻahaʻa. .ʻO ka hōʻike ʻana a hiki i 6 mau hola i kēlā me kēia lā, 5 mau lā i kēlā me kēia pule, no 5 mau pule i ukali ʻia e ka necropsy, ke kaumaha o ke kino a me ka loiloi histopathological.
Ua hōʻike ʻia nā hopena hōʻike hope loa i ka hoʻohālikelike ʻia me ka ʻike ʻana i ka uahi paka, ʻo nā ʻiole i ʻike ʻia i nā aerosol e-cigarette me nā mea ʻono ʻole a ʻaʻohe hoʻololi koʻikoʻi i loko o nā ʻōpū hanu, ihu, a me ka laryngeal epithelial tissues. i nā ʻiʻo a me nā ʻāpana pili.Ua hōʻoia hou nā hopena hoʻokolohua, i ka hoʻohālikelike ʻia me nā paka kuʻuna, hiki i ka e-cigarettes ke hoʻemi nui i ka mumū o ka māmā, a me ka pōʻino i ka epithelium o ka ihu, ka puʻu a me ka trachea.
Ua hoʻopuka ʻo BAT British American Tobacco i kahi pepa noiʻi i kapa ʻia ʻo "An Experimental Analytical and In Vitro Approach to Bridge Between Different Heated Tobacco Product Variants" ma ka "Contributions to Tobacco & Nicotine Research" ʻepekema puke pai, a ua alakaʻi i kahi noiʻi ma THP (HNB huahana) Toxicology hoao ana.I ka hoʻokolohua, ua hoʻohana ʻia ka aerosol a me ka uahi paka o ʻelima mau ʻano o THP a me hoʻokahi THP kumu ma ke ʻano hoʻokolohua, a ua loiloi ʻia ka cytotoxicity e ka viability o nā pūnana epithelial lung kanaka.Ua hōʻike nā hopena i nā hopena cytotoxic a pau i ka hui THP ma kahi o 95% haʻahaʻa ma mua o ka poʻe i loko o ka hui uahi paka, a ʻaʻohe ʻokoʻa nui o ka ʻona ma waena o nā THP ʻano ʻelima a me ka THP kumu.
Ua hoʻoholo ka haʻawina e ulu wikiwiki ana ka hoʻomohala ʻana a me ka hoʻolako ʻana i nā paka a me nā huahana nicotine, ke ʻae nei nā mea kūʻai aku i nā huahana hou e like me THP, a ʻo kona palekana a me ka pilikia ma ke ʻano o ka loiloi toxicological pono e nānā i ka ʻoihana.Ke kū wale ka huahana i nā kūlana (me ka hana ʻana i ka pākaukau) hiki iā ia ke hoʻokani maikaʻi i kāna kūlana maikaʻi ma ke ʻano he hoʻolālā olakino lehulehu.
Kuhikuhi:
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, a me al.Ka loiloi o ka inhalation o ka uahi paka a me nā aerosol mai nā hui ʻono: 5-week study i nā ʻiole A/J.Nūpepa o ka toxicolog i noi ʻia, 2022
Tomasz Jaunky, David Thorne, Andrew Baxter, a me al.ʻO kahi ʻano hoʻokolohua hoʻāʻo a me In Vitro i ke alahaka ma waena o nā ʻano huahana paka wela.Nā Haʻawina i ka ʻImi Paka a me Nikotini, 2022.
Ka manawa hoʻouna: Feb-01-2023
